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  • Dr. Jordan Weinstein's reply was accepted as an answer
    Lupus Nephritis
    Hi Venkat,

    In some ways you have answered your own question. If the patient is responding, then the regimen is reasonable in her case. In general as well, MMF is likely equivalent to cyclophosphamide for the treatment of lupus nephritis....
    Hi Venkat,

    In some ways you have answered your own question. If the patient is responding, then the regimen is reasonable in her case. In general as well, MMF is likely equivalent to cyclophosphamide for the treatment of lupus nephritis. Having said that, some do reserve MMF more-so for cases with more benign histopathology and use cyclophosphamide for more severe cases. The evidence for this approach is not sound in my opinion - that is to say, that cyclophosphamide would be superior to MMF in more severe cases of lupus nephritis. Yet, this practice is widespread.

    I include 3 references below which you are likely familiar with.

    Dr. Jordan Weinstein
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  • venkat replied to a discussion, Lupus Nephritis
    Dear Dr. Weinstein

    Greetings !

    Thank you for the prompt reply and sharing current evidence on the subject, very reassuring :) ....

    warm regards
    Venkat
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  • Dr. Jordan Weinstein replied to a discussion, Lupus Nephritis
    Hi Venkat,

    In some ways you have answered your own question. If the patient is responding, then the regimen is reasonable in her case. In general as well, MMF is likely equivalent to cyclophosphamide for the treatment of lupus nephritis....
    Hi Venkat,

    In some ways you have answered your own question. If the patient is responding, then the regimen is reasonable in her case. In general as well, MMF is likely equivalent to cyclophosphamide for the treatment of lupus nephritis. Having said that, some do reserve MMF more-so for cases with more benign histopathology and use cyclophosphamide for more severe cases. The evidence for this approach is not sound in my opinion - that is to say, that cyclophosphamide would be superior to MMF in more severe cases of lupus nephritis. Yet, this practice is widespread.

    I include 3 references below which you are likely familiar with.

    Dr. Jordan Weinstein
    More
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